Searchable abstracts of presentations at key conferences in endocrinology

ea0029p1109 | Neuroendocrinology | ICEECE2012

Investigating glucose responsive neuropeptide release using a static hypothalamic incubation system

Hussain S. , Richardson E. , Bewick G. , Bloom S. , Gardiner J.

The activity of certain hypothalamic neuronal populations is altered by changes in glucose. in-vitro studies have identified several glucose-sensitive neuronal populations in hypothalamic regions controlling energy homeostasis. Subsets of orexigenic arcuate nucleus Neuropeptide Y (NPY)-releasing neurones are known to be glucose responsive. These neurones may allow glucose to influence appetite. Cocaine and amphetamine regulated transcript (CART) is a neurotransmitter ab...